| Product name: |
CD236 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Glycophorin-C (Glycoconnectin;Glycophorin-D;GPD;Glycoprotein beta;PAS-2′;Sialoglycoprotein D;CD antigen CD236) |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, ELISA 1:10000-20000 |
| Immunogen: |
Synthetic peptide from human protein at AA range: 11-60 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| GeneID: |
2995 |
| Human Swiss-Prot No: |
P04921 |
| Cellular localization: |
Cell membrane; Single-pass type III membrane protein. Linked to the membrane via band 4.1. |
| Background: |
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012], |
