| Product name: |
HDGF rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Hepatoma-derived growth factor (HDGF;High mobility group protein 1-like 2;HMG-1L2) |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, ELISA 1:10000-20000 |
| Immunogen: |
Synthetic peptide from human protein at AA range: 141-190 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| GeneID: |
3068 |
| Human Swiss-Prot No: |
P51858 |
| Cellular localization: |
[Isoform 1]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located inside the exosome (PubMed:27926477). May also be secreted as free protein via an as yet unknown pathway (PubMed:27926477). .; [Isoform 2]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located on the outer exosome surface. .; [Isoform 3]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located on the outer exosome surface. . |
| Background: |
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016], |
