| Product name: |
COL8A2 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
Collagen alpha-2(VIII) chain (Endothelial collagen) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen: |
Synthesized peptide derived from human COL8A2. at AA range: 611-660 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
80kD |
| GeneID: |
1296 |
| Human Swiss-Prot No: |
P25067 |
| Cellular localization: |
Secreted, extracellular space, extracellular matrix, basement membrane. |
| Background: |
This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014], |
