| Product name: |
MYH6 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: |
Synthesized peptide derived from human MYH6. at AA range: 341-390 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
200kD |
| GeneID: |
4624 |
| Human Swiss-Prot No: |
P13533 |
| Cellular localization: |
Cytoplasm, myofibril. Thick filaments of the myofibrils. |
| Background: |
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located ~4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3. [provided by RefSeq, Mar 2010], |
