| Product name: |
TRI63 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from part region of human protein |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
38kD |
| GeneID: |
84676 |
| Human Swiss-Prot No: |
Q969Q1 |
| Cellular localization: |
Cytoplasm. Nucleus . Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, myofibril, sarcomere, Z line. Colocalizes with TNNI3 in myocytes (By similarity). Localizes to the M- and Z-lines in skeletal muscle. . |
| Background: |
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012], |
