| Product name: |
MY18A rabbit pAb |
| Reactivity: |
Human;Mouse |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human protein . at AA range: 1920-2000 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
225kD |
| GeneID: |
399687 |
| Human Swiss-Prot No: |
Q92614 |
| Cellular localization: |
Golgi apparatus . Golgi apparatus, trans-Golgi network . Golgi outpost . Cytoplasm, cytoskeleton, microtubule organizing center . Recruited to the Golgi apparatus by GOLPH3 (PubMed:19837035). Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). .; [Isoform 1]: Endoplasmic reticulum-Golgi intermediate compartment . Cytoplasm, cytoskeleton . Colocalizes with actin. .; [Isoform 2]: Cytoplasm . Lacks the PDZ domain (PubMed:12761286). Diffusely localized in the cytoplasm (PubMed:12761286). .; [Isoform 5]: Cell surface . |
| Background: |
caution:The TIAF1 protein is coded in the 3′-UTR region of MYO18A.,function:May be involved in the maintenance of the stromal cell architectures required for cell to cell contact.,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Colocalizes with actin.,subcellular location:Lacks the PDZ domain. Diffusely localized in the cytoplasm.,subunit:Homodimer. Interacts with JAK3 and actin., |