| Product name: |
OPA1 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from part region of human protein |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
105kD |
| GeneID: |
4976 |
| Human Swiss-Prot No: |
O60313 |
| Cellular localization: |
Mitochondrion inner membrane ; Single-pass membrane protein . Mitochondrion intermembrane space . Mitochondrion membrane . Detected at contact sites between endoplasmic reticulum and mitochondrion membranes. . |
| Background: |
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009], |
