| Cellular localization: |
Nucleus outer membrane ; Single-pass type IV membrane protein ; Cytoplasmic side . Sarcoplasmic reticulum membrane ; Single-pass type IV membrane protein . Cell membrane ; Single-pass membrane protein . Cytoplasm, cytoskeleton. Mitochondrion. Nucleus, nucleoplasm. Cytoplasm, myofibril, sarcomere, Z line . Different isoform patterns are found in the different compartments of the cell. The isoforms having the C-terminal transmembrane span can be found in several organellar membranes like the nuclear envelope, the sarcoplasmic reticulum of myoblasts, or the lamellipodia and focal adhesions at the cell membrane. The largest part of the outer nuclear membrane-associated protein is cytoplasmic, while its C-terminal part is associated with the nuclear envelope, most probably the outer nuclear mem |
