| Product name: |
BTF rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
BCLAF1; BTF; KIAA0164; Bcl-2-associated transcription factor 1; Btf |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human BCLAF1. AA range:281-330 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
106kD |
| GeneID: |
9774 |
| Human Swiss-Prot No: |
Q9NYF8 |
| Cellular localization: |
Cytoplasm. Nucleus. Nucleus speckle . Nucleus, nucleoplasm . |
| Background: |
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |