| Product name: |
PICK1 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from part region of human protein |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
45kD |
| GeneID: |
9463 |
| Human Swiss-Prot No: |
Q9NRD5 |
| Cellular localization: |
Cytoplasm, perinuclear region. Membrane ; Peripheral membrane protein . Membrane ; Lipid-anchor . Cell junction, synapse, postsynaptic density . Cell junction, synapse, synaptosome . Cytoplasm, cytoskeleton . Also membrane-associated, present at excitatory synapses. . |
| Background: |
protein interacting with PRKCA 1(PICK1) Homo sapiens The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008], |
