| Product name: |
HBB rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from part region of human protein |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
16kD |
| GeneID: |
3043 |
| Human Swiss-Prot No: |
P68871 |
| Cellular localization: |
extracellular region,cytosol,hemoglobin complex,integral component of membrane,haptoglobin-hemoglobin complex,extracellular exosome,endocytic vesicle lumen,blood microparticle, |
| Background: |
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5′-epsilon — gamma-G — gamma-A — delta — beta–3′. [provided by RefSeq, Jul 2008], |
