5HT3B rabbit pAb – TO11451
TO11451
Size:Price:
50 µL$148.00
100 µL$248.00

Overview

Product name: 5HT3B rabbit pAb
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 140-220
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 48kD
GeneID: 9177
Human Swiss-Prot No: O95264
Cellular localization: Cell membrane ; Multi-pass membrane protein . Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
Background: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011],