Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Source:
Rabbit
Dilutions:
WB 1:500-2000;IHC-p 1:50-300
Immunogen:
Synthesized phosho peptide around human Rictor (Thr1135)
Storage:
-20C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
190kD
GeneID:
253260
Human Swiss-Prot No:
Q6R327
Cellular localization:
cytosol,TORC2 complex,
Background:
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008],