Glutaredoxin-1 Polyclona Antibody – TO16159
TO16159
Size:Price:
50 µL$148.00
100 µL$248.00

Overview

Product name: Glutaredoxin-1 Polyclona Antibody
Reactivity: Human;Rat;Mouse;
Alternative Names: Glutaredoxin-1 (Thioltransferase-1;TTase-1)
Source: Rabbit
Dilutions: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from human Glutaredoxin-1 AA range: 8-58
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 2745
Human Swiss-Prot No: P35754
Cellular localization: Cytoplasm.
Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer’s disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011],