| Background: |
alternative products:Experimental confirmation may be lacking for some isoforms,function:Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.,PTM:Phosphorylated on tyrosines by SRC.,similarity:Belongs to the CAS family.,similarity:Contains 1 SH3 domain.,subunit:Interacts (via SH3 domain) with focal adhesion kinase (via C-terminus).,tissue specificity:Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines., |
