| Product name: |
TORC1/CRTC1 (phospho-Ser151) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1000-2000 |
| Immunogen: |
Synthesized phosho peptide around human TORC1 and CRTC1 (Ser151) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
70kD |
| GeneID: |
23373 |
| Human Swiss-Prot No: |
Q6UUV9 |
| Cellular localization: |
Cytoplasm . Nucleus . Cytoplasmic when phosphorylated by SIK or AMPK and when sequestered by 14-3-3 proteins (PubMed:16817901). Translocated to the nucleus on Ser-151 dephosphorylation, instigated by a number of factors including calcium ion and cAMP levels (PubMed:15589160). Light stimulation triggers a nuclear accumulation in the suprachiasmatic nucleus (SCN) of the brain (By similarity). . |
