| Product name: |
ATD3A rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human ATD3A AA range: 433-483 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
70kD |
| GeneID: |
55210 |
| Human Swiss-Prot No: |
Q9NVI7 |
| Cellular localization: |
Mitochondrion inner membrane ; Single-pass membrane protein . Mitochondrion matrix, mitochondrion nucleoid . In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane (PubMed:20349121, PubMed:20154147). The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (PubMed:18063578). . |
| Background: |
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008], |