| Product name: |
SPG16 rabbit pAb |
| Reactivity: |
Human; Mouse |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: |
Synthesized peptide derived from human SPG16 AA range: 520-570 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
69kD |
| GeneID: |
79582 |
| Human Swiss-Prot No: |
Q8N0X2 |
| Cellular localization: |
Cytoplasm . Cytoplasm, cytoskeleton, flagellum axoneme . Cytoplasm, cytoskeleton, cilium axoneme . Cell projection, cilium, flagellum . Detected on the sperm flagellum axoneme. Detected in the central apparatus of the axoneme. Colocalizes with SPAG6 on microtubules (By similarity). . |
| Background: |
Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 [PubMed 17699735]).[supplied by OMIM, Jul 2008], |
