SHOX2 rabbit pAb – TO13119
TO13119
Size:Price:
50 µL$148.00
100 µL$248.00
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Overview

Product name: SHOX2 rabbit pAb
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300,FCM 1:100-200
Immunogen: Synthesized peptide derived from human SHOX2 AA range: 37-87
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 36kD
GeneID: 6474
Human Swiss-Prot No: O60902
Cellular localization: Nucleus.
Background: This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],