SESN3 rabbit pAb – TO13146
TO13146
Size:Price:
50 µL$148.00
100 µL$248.00

Overview

Product name: SESN3 rabbit pAb
Reactivity: Human; Mouse
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized peptide derived from human SESN3 AA range: 35-85
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 54kD
GeneID: 143686
Human Swiss-Prot No: P58005
Cellular localization: Cytoplasm .
Background: This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],