| Product name: |
SEC61B Polyclona Antibody |
| Reactivity: |
Human; Mouse; Rat |
| Alternative Names: |
Protein transport protein Sec61 subunit beta |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, ELISA(peptide)1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human SEC61B AA range: 30-110 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| GeneID: |
10952 |
| Human Swiss-Prot No: |
P60468 |
| Cellular localization: |
Endoplasmic reticulum membrane ; Single-pass membrane protein . |
| Background: |
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008], |
