| Product name: |
REPS1 (phospho-Ser709) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: |
Synthesized phosho peptide around human REPS1 (Ser709) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
80kD |
| GeneID: |
85021 |
| Human Swiss-Prot No: |
Q96D71 |
| Cellular localization: |
Membrane, clathrin-coated pit . Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits. |
| Background: |
This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014], |
