| Product name: |
EOMES rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
73kD |
| GeneID: |
8320 |
| Human Swiss-Prot No: |
O95936 |
| Cellular localization: |
Nucleus . |
| Background: |
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013], |
