| Product name: |
POLD4 Polyclona Antibody |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
DNA polymerase delta subunit 4 (DNA polymerase delta subunit p12) |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from human POLD4 AA range: 43-93 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| GeneID: |
57804 |
| Human Swiss-Prot No: |
Q9HCU8 |
| Cellular localization: |
Nucleus . Partially recruited to DNA damage sites within 2 hours following UV irradiation, before degradation. . |
| Background: |
This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3′ to 5′ exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012], |
