| Product name: |
ERCC4 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
ERCC4; ERCC11; XPF; DNA repair endonuclease XPF; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human XPF. AA range:801-850 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
103kD |
| GeneID: |
2072 |
| Human Swiss-Prot No: |
Q92889 |
| Cellular localization: |
Nucleus . Chromosome . Localizes to sites of DNA damage. . |
| Background: |
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5′ incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009], |
