| Product name: |
PARG rabbit pAb |
| Reactivity: |
Human; Mouse;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human PARG AA range: 140-190 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
107kD |
| GeneID: |
8505 |
| Human Swiss-Prot No: |
Q86W56 |
| Cellular localization: |
[Isoform 1]: Nucleus . Colocalizes with PCNA at replication foci (PubMed:21398629). Relocalizes to the cytoplasm in response to DNA damage (PubMed:16460818). .; [Isoform 2]: Cytoplasm . Translocates to the nucleus in response to DNA damage. .; [Isoform 3]: Cytoplasm .; [Isoform 4]: Cytoplasm . Mitochondrion .; [Isoform 5]: Mitochondrion matrix . |
| Background: |
This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009], |
