| Product name: |
-actinin Rabbit pAb |
| Reactivity: |
Rat, Mouse |
| Alternative Names: |
actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoidrepeatedfreeze-thawcycles. |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1mg/mL |
| Observed Band: |
103kDa |
| GeneID: |
87 |
| Human Swiss-Prot No: |
P12814 |
| Cellular localization: |
Cell junction,Cell membrane,Cell projection,Cytoplasm,Cytoskeleton,Membrane |
| Background: |
-Actinin belongs to the spectrin family of cytoskeletal proteins. -Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis. |
