| Product name: |
4.1R (phospho Tyr660) rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
EPB41; E41P; Protein 4.1; P4.1; 4.1R; Band 4.1; EPB4.1 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human EPB41 around the phosphorylation site of Tyr660/418. AA range:626-675 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
60kD |
| GeneID: |
2035 |
| Human Swiss-Prot No: |
P11171 |
| Cellular localization: |
Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Nucleus . |
| Background: |
The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Oct 2009], |
