| Product name: |
Active Caspase 3 Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody |
| Source: |
Mouse |
| Dilutions: |
WB 1:500-1,000 IHC 1:100-200 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
17kDa |
| GeneID: |
836 |
| Human Swiss-Prot No: |
P42574 |
| Cellular localization: |
Cytoplasm |
| Background: |
Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position. |
