| Product name: |
Adenosine A1-R rabbit pAb |
| Reactivity: |
Human;Rat |
| Alternative Names: |
ADORA1; Adenosine receptor A1 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human ADORA1. AA range:277-326 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
37kD |
| GeneID: |
134 |
| Human Swiss-Prot No: |
P30542 |
| Cellular localization: |
Cell membrane ; Multi-pass membrane protein. |
| Background: |
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5′ UTR have been found for this gene. [provided by RefSeq, Jul 2008], |
