| Product name: |
AHR rabbit pAb |
| Reactivity: |
Human; Mouse;Rat;Fish |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000; IF/ICC 1:100-500 |
| Immunogen: |
Synthesized peptide derived from human AHR AA range: 408-458 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
93kD |
| GeneID: |
196 |
| Human Swiss-Prot No: |
P35869 |
| Cellular localization: |
Cytoplasm . Nucleus . Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. . |
| Background: |
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015], |
