| Product name: |
Arylsulfatase A rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
ARSA; Arylsulfatase A; ASA; Cerebroside-sulfatase |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human ARSA. AA range:251-300 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
54kD |
| GeneID: |
410 |
| Human Swiss-Prot No: |
P15289 |
| Cellular localization: |
Endoplasmic reticulum . Lysosome . |
| Background: |
The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010], |
