| Product name: |
Bcl-2 (phospho Thr74) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
BCL2; Apoptosis regulator Bcl-2 |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
Synthesized phospho-peptide around the phosphorylation site of human Bcl-2 (phospho Thr74) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
26kD |
| GeneID: |
596 |
| Human Swiss-Prot No: |
P10415 |
| Cellular localization: |
Mitochondrion outer membrane ; Single-pass membrane protein . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Cytoplasm . |
| Background: |
BCL2, apoptosis regulator(BCL2) Homo sapiens This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016], |
