| Product name: |
BCL3 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse;;Goat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human protein . at AA range: 340-420 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
49kD |
| GeneID: |
602 |
| Human Swiss-Prot No: |
P20749 |
| Cellular localization: |
Nucleus. Cytoplasm . Cytoplasm, perinuclear region . Ubiquitination via ‘Lys-63’-linked ubiquitin chains is required for nuclear accumulation. . |
| Background: |
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008], |
