Synthesized peptide derived from human protein . at AA range: 1280-1360
Storage:
-20C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
335kD
GeneID:
259282
Human Swiss-Prot No:
Q8NFC6
Cellular localization:
Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. .
Background:
Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM.
