| Product name: |
Beclin-1 (5C2) Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
ATG6, Bcl-2 interacting protein beclin, BECN1, Coiled coil myosin like BCL2 interacting protein |
| Source: |
Mouse |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
60kDa |
| GeneID: |
8678 |
| Human Swiss-Prot No: |
Q14457 |
| Cellular localization: |
Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Mitochondrion, Nucleus |
| Background: |
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of proteins activated in response to nutrient deprivation and in neurodegenerative conditions. One of the proteins critical to this process is Beclin-1. |
