| Product name: |
BEST2 rabbit pAb |
| Reactivity: |
Mouse;Rat |
| Alternative Names: |
Bestrophin-2; Vitelliform macular dystrophy 2-like protein 1 |
| Source: |
Rabbit |
| Dilutions: |
WB: 1:500-1000 IHC: 1:200-500 |
| Immunogen: |
Synthetic Peptide of BEST2 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Observed Band: |
50kD |
| GeneID: |
54831 |
| Human Swiss-Prot No: |
Q8NFU1 |
| Cellular localization: |
Cell membrane; Multi-pass membrane protein. |
| Background: |
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3′ ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008], |
