| Product name: |
BFSP1 rabbit pAb |
| Reactivity: |
Human; Mouse;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human BFSP1 AA range: 494-544 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
73kD |
| GeneID: |
631 |
| Human Swiss-Prot No: |
Q12934 |
| Cellular localization: |
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . |
| Background: |
This gene encodes a lens-specific intermediate filament-like protein named filensin. The encoded protein is expressed in lens fiber cells after differentiation has begun. This protein functions as a component of the beaded filament which is a cytoskeletal structure found in lens fiber cells. Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
