| Product name: |
CALHM1 rabbit pAb |
| Reactivity: |
Human;Rat |
| Alternative Names: |
Calcium homeostasis modulator protein 1; Protein FAM26C |
| Source: |
Rabbit |
| Dilutions: |
WB: 1:500-1000 IHC: 1:200-500 |
| Immunogen: |
Synthetic Peptide of CALHM1 AA range: 204-254 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Observed Band: |
40kD |
| GeneID: |
255022 |
| Human Swiss-Prot No: |
Q8IU99 |
| Cellular localization: |
Cell membrane; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein . Colocalizes with HSPA5 at the endoplasmic reticulum (PubMed:18585350). Localizes to the basolateral membrane of epithelial cells including taste cells (By similarity). . |
| Background: |
calcium homeostasis modulator 1(CALHM1) Homo sapiens This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer’s disease in some populations, but the pathogenicity of this polymorphism is unclear.[provided by RefSeq, Mar 2010], |
