| Product name: |
Caspase 3 Rabbit pAb |
| Reactivity: |
Human |
| Alternative Names: |
APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoidrepeatedfreeze-thawcycles. |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1mg/mL |
| Observed Band: |
32kDa |
| GeneID: |
836 |
| Human Swiss-Prot No: |
P42574 |
| Cellular localization: |
Cytoplasm |
| Background: |
Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP). |
