| Product name: |
CCL17 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
C-C motif chemokine 17 (CC chemokine TARC;Small-inducible cytokine A17;Thymus and activation-regulated chemokine) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000, ELISA(peptide)1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human CCL17 AA range: 21-70 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
10kD |
| GeneID: |
6361 |
| Human Swiss-Prot No: |
Q92583 |
| Cellular localization: |
Secreted. |
| Background: |
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014], |
