| Product name: |
Cleaved-Thrombin R (S42) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
F2R; CF2R; PAR1; TR; Proteinase-activated receptor 1; PAR-1; Coagulation factor II receptor; Thrombin receptor |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human PAR1. AA range:23-72 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
46kD |
| GeneID: |
2149 |
| Human Swiss-Prot No: |
P25116 |
| Cellular localization: |
Cell membrane; Multi-pass membrane protein. |
| Background: |
Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015], |
