| Product name: |
CLIC1 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse |
| Alternative Names: |
Chloride intracellular channel protein 1 (Chloride channel ABP;Nuclear chloride ion channel 27;NCC27;Regulatory nuclear chloride ion channel protein;hRNCC) |
| Source: |
Rabbit |
| Dilutions: |
IHC 1:100-200 |
| Immunogen: |
Synthetic Peptide of CLIC1 AA range: 166-216 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
30kD |
| GeneID: |
1192 |
| Human Swiss-Prot No: |
O00299 |
| Cellular localization: |
Nucleus . Nucleus membrane ; Single-pass membrane protein . Cytoplasm . Cell membrane ; Single-pass membrane protein . Mostly in the nucleus including in the nuclear membrane (PubMed:9139710, PubMed:12681486). Small amount in the cytoplasm and the plasma membrane (PubMed:9139710). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (PubMed:11940526, PubMed:11551966, PubMed:14613939). . |
| Background: |
chloride intracellular channel 1(CLIC1) Homo sapiens Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008], |
