| Product name: |
COL11A1 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
COL11A1; COLL6; Collagen alpha-1(XI) chain |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human Collagen XI alpha1. AA range:581-630 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
181kD |
| GeneID: |
1301 |
| Human Swiss-Prot No: |
P12107 |
| Cellular localization: |
Secreted, extracellular space, extracellular matrix . |
| Background: |
collagen type XI alpha 1 chain(COL11A1) Homo sapiens This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009], |