| Product name: |
CRM1 (Acetyl Lys568) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568. |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
125kD |
| GeneID: |
7514 |
| Human Swiss-Prot No: |
O14980 |
| Cellular localization: |
Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm. |
| Background: |
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015], |
