| Product name: |
CSPG4 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-300 |
| Immunogen: |
Synthesized peptide derived from human protein . at AA range: 1910-1990 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
255kD |
| GeneID: |
1464 |
| Human Swiss-Prot No: |
Q6UVK1 |
| Cellular localization: |
Cell membrane ; Single-pass type I membrane protein ; Extracellular side . Apical cell membrane ; Single-pass type I membrane protein ; Extracellular side . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein ; Extracellular side . Cell surface . Localized at the apical plasma membrane it relocalizes to the lamellipodia of astrocytoma upon phosphorylation by PRKCA. Localizes to the retraction fibers. Localizes to the plasma membrane of oligodendrocytes (By similarity). . |
| Background: |
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. [provided by RefSeq, Jul 2008], |
