| Product name: |
DFNA5 rabbit pAb |
| Reactivity: |
Human;Rat |
| Alternative Names: |
DFNA5; ICERE1; Non-syndromic hearing impairment protein 5; Inversely correlated with estrogen receptor expression 1; ICERE-1 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from DFNA5 . at AA range: 200-280 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
54kD |
| GeneID: |
1687 |
| Human Swiss-Prot No: |
O60443 |
| Cellular localization: |
[Gasdermin-E, N-terminal]: Cell membrane ; Multi-pass membrane protein .; [Gasdermin-E]: Cytoplasm, cytosol . |
| Background: |
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
