| Product name: |
DOC2A rabbit pAb |
| Reactivity: |
Human; Mouse;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human DOC2A AA range: 22-72 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
44kD |
| GeneID: |
8448 |
| Human Swiss-Prot No: |
Q14183 |
| Cellular localization: |
Lysosome . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Peripheral membrane protein . Cell junction, synapse, synaptosome. |
| Background: |
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013], |
