| Product name: |
Dyrk1B rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
DYRK1B; MIRK; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Minibrain-related kinase; Mirk protein kinase |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human DYR1B. AA range:331-380 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
70kD |
| GeneID: |
9149 |
| Human Swiss-Prot No: |
Q9Y463 |
| Cellular localization: |
Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of double-strand breaks (DSBs) following DNA damage. . |
| Background: |
This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014], |
