| Product name: |
E-Ras rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human ERAS. AA range:184-233 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
25kD |
| GeneID: |
3266 |
| Human Swiss-Prot No: |
Q7Z444 |
| Cellular localization: |
Cell membrane ; Lipid-anchor ; Cytoplasmic side . |
| Background: |
This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012], |
